Table 1.
Summary of patient characteristics and measurements between diaphragm motion and liver tumor motion evaluated by PDP, ICC, and Bland-Altman analysis from all patient subjects
| PDP (%)
|
ICC
|
Bland-Altman analysis
|
||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Patient | Age (y) | Sex | Cancer site | SI | AP | ML | SI
|
AP
|
ML | SI
|
AP
|
ML
|
||||||
| ICC | 95% CI | ICC | 95% CI | ICC | 95% CI | Diff (mm) | 95% CI | Diff (mm) | 95% CI | Diff (mm) | 95% CI | |||||||
| 1 | 70 | M | HCC | 6.5 | 4.5 | 20.5 | 0.99 | 0.98–0.99 | 0.99 | 0.93–0.96 | 0.18 | −0.28–0.29 | 0.8 | −1.46–1.46 | 0.3 | −1.29–1.29 | 1.6 | −0.87–0.87 |
| 2 | 68 | F | HCC | 6.8 | 4.8 | 15.2 | 0.98 | 0.97–0.99 | 0.98 | 0.95–0.98 | 0.1 | −0.20–0.35 | 2.0 | −1.68–1.75 | 2.2 | −1.28–1.32 | 1.8 | −0.56–0.55 |
| 3 | 67 | F | HCC | 6.0 | 5.2 | 15.0 | 0.96 | 0.96–0.99 | 0.95 | 0.95–0.99 | 0.04 | −0.26–0.30 | 4.2 | −1.52–1.55 | 3.4 | −1.30–1.30 | 2.6 | −0.88–0.78 |
| 4 | 34 | F | HCC | 7.0 | 4.9 | 25.6 | 0.98 | 0.96–1.00 | 0.96 | 0.98–0.99 | 0.06 | −0.40–0.45 | 3.5 | −1.50–1.80 | 3.2 | −1.22–1.50 | 2.5 | −0.85–0.79 |
| 5 | 68 | F | HCC | 6.5 | 4.0 | 15.8 | 0.96 | 0.98–1.00 | 0.96 | 0.98–1.00 | 0.05 | −0.22–0.28 | 3.8 | −1.34–1.42 | 3.2 | −1.28–1.24 | 2.6 | −0.77–0.69 |
| 6 | 67 | M | Liver Mets | 8.0 | 5.5 | 16.0 | 0.94 | 0.93–0.98 | 0.95 | 0.96–0.98 | 0.04 | −0.24–0.28 | 4.5 | −1.42–1.45 | 3.4 | −1.26–1.26 | 2.7 | −0.82–1.05 |
| 7 | 55 | M | HCC | 6.0 | 3.2 | 24.5 | 0.96 | 0.99–1.00 | 0.96 | 0.94–0.97 | 0.05 | −0.35–0.48 | 4.0 | −1.38–1.47 | 3.3 | −1.26–1.25 | 2.6 | −0.90–1.14 |
| 8 | 54 | M | HCC | 6.5 | 4.7 | 21.5 | 0.98 | 0.92–0.99 | 0.96 | 0.95–0.96 | 0.09 | −0.52–0.54 | 2.6 | −1.35–1.49 | 2.4 | −1.27–1.27 | 1.9 | −0.88–1.00 |
| 9 | 60 | F | HCC | 7.6 | 4.9 | 18.5 | 0.99 | 0.95–0.99 | 0.98 | 0.95–0.97 | 0.12 | −0.40–0.65 | 1.5 | −1.42–1.46 | 1.3 | −1.30–1.27 | 1.7 | −0.79–0.92 |
| 10 | 73 | M | HCC | 7.0 | 5.0 | 17.0 | 0.99 | 0.95–0.99 | 0.98 | 0.96–0.98 | 0.04 | −0.21–0.30 | 1.0 | −1.54–1.80 | 1.2 | −1.32–1.26 | 1.7 | −0.54–0.65 |
| 11 | 22 | M | Liver Mets | 8.8 | 4.3 | 13.4 | 0.99 | 0.98–1.00 | 0.98 | 0.97–0.99 | 0.16 | −0.65–0.85 | 0.8 | −2.90–2.90 | 1 | −3.20–3.20 | 1.7 | −2.50–2.50 |
| 12 | 55 | F | Liver Mets | 6.2 | 4.2 | 12.0 | 0.98 | 0.98–1.00 | 0.96 | 0.92–0.95 | 0.07 | −0.52–0.50 | 3.5 | −1.84–1.72 | 2.8 | −1.20–1.22 | 2.4 | −0.79–0.82 |
| 13 | 62 | M | Liver Mets | 5.4 | 4.0 | 10.5 | 0.92 | 0.99–1.00 | 0.94 | 0.99–1.00 | 0.01 | −0.38–0.20 | 4.6 | −1.30–1.40 | 3.5 | −1.24–1.20 | 2.8 | −0.80–1.04 |
| 14 | 75 | F | HCC | 7.2 | 4.5 | 20.1 | 0.99 | 0.95–0.99 | 0.96 | 0.98–0.99 | 0.09 | −0.43–0.35 | 3.0 | −1.34–1.43 | 2.5 | −1.25–1.30 | 2.4 | −0.72–0.65 |
| Mean | 61 | — | — | 7.1 | 4.5 | 17.5 | 0.98 | — | 0.97 | — | 0.08 | — | 2.8 | — | 2.4 | — | 2.2 | — |
| SD | 15 | — | — | 1.1 | 0.5 | 4.5 | 0.02 | — | 0.02 | — | 0.06 | — | 1.4 | — | 1.1 | — | 0.5 | — |
Abbreviations: AP = anterior–posterior; CI = confidence interval; Diff = difference in motion amplitude; F = female; HCC = hepatocellular carcinoma; ICC = intraclass coefficient correlation; Liver Mets = liver metastasis; M = male; ML = medial–lateral; PDP = phase difference percentage; SD = standard deviation; SI = superior–inferior.