Figure 4. Treatment with NF-κB Inhibitors Rescues Dendritic Complexity following Cc2d1a Knockdown.
(A) In independent experiments, hippocampal neurons were treated with NF-κB inhibitor JSH-23 (top panels) or NF-κB inhibitor SN50 and the inactive control peptide SN50m (bottom panels). Scale bar, 50 μm.
(B) Dendrite number quantification shows that both inhibitors restore dendritic complexity in hippocampal cultures (n = 4 for each inhibitor). All graphs show mean ± SEM. **p < 0.01; ***p < 0.001; n.s., not significant.