Table 1.
Transplantation route | Transplanted cell number | Cardiac retention | Lung retention |
---|---|---|---|
Intra-myocardial injection | |||
Permanent ligation (PL), n = 15 Cell transplantation immediately following ligation |
2 × 106 | 22.9% ± 5.2% | 28.5% ± 5.0% |
Acute ischemia-reperfusion (AI-RM), n = 17 Ischemia for 45 minutes followed by reperfusion and immediate cell transplantation |
2 × 106 | 12.0% ± 3.9% | 39.9% ± 9.3% |
Normal (NL), n = 10 Cell transplantation without infarction |
2 × 106 | 13.6% ± 2.3% | 43.3% ± 5.6% |
Chronic ischemia-reperfusion (CI-R), n = 13 Ischemia for 45 minutes followed by reperfusion; cell transplantation 30 days after reperfusion |
2 × 106 | 9.9 ± 2.8 | 20.2% ± 9.3% |
Intracoronary (intra-cavitary) injection | |||
Acute ischemia-reperfusion (AI-RC), n = 5 Ischemia for 45 minutes followed by reperfusion and immediate cell transplantation |
1 × 106 | 15.4% ± 5.5% | 19.9% ± 5.6% |
Intravenous injection | |||
Acute ischemia-reperfusion (AI-RV), n = 10 Ischemia for 45 minutes followed by reperfusion and immediate cell transplantation |
5 × 106 | 0.8% ± 1.06% | 55.1% ± 9.3% |