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. Author manuscript; available in PMC: 2015 Mar 15.
Published in final edited form as: Anal Biochem. 2013 Dec 19;449:68–75. doi: 10.1016/j.ab.2013.12.018

Figure 6. Inhibition profile of insect- and mammalian-expressed ADAM17_ECD.

Figure 6

(A) ADAM17_ECD inhibition by N-acetohydroxamic acid; (B) ADAM17_ECD inhibition by TAPI-2; (C) ADAM17_ECD inhibition by compound #15 using substrate #4 ((EDANS) E-PLAQAVRSS*S-K (DABCYL). Note: * - glycosylation); (D) ADAM17_ECD inhibition by compound #15 using substrate ES010 (Mca-KPLGL-Dpa-AR-NH2).