Table 1. Changes in DMN (rest > task) BOLD signal following Ayahuasca intake.
β-values Before Ayahuasca | β-values After Ayahuasca | ||||||
---|---|---|---|---|---|---|---|
ROI | Nvoxel | Mean | SD | Mean | SD | P value | |
ACC | 606 | 0.4193 | 0.2797 | 0.3188 | 0.1497 | < 0.0001 | * |
PCC | 2058 | 0.6409 | 0.3636 | 0.5378 | 0.2397 | < 0.0001 | * |
MPFC | 2963 | 0.551 | 0.3701 | 0.4211 | 0.2854 | < 0.0001 | * |
RIPL | 3216 | 0.5226 | 0.2997 | 0.4620 | 0.2612 | < 0.0001 | * |
LIPL | 1749 | 0.4464 | 0.2650 | 0.3795 | 0.2392 | < 0.0001 | * |
LMFG | 98 | 0.0798 | 0.0830 | 0.2140 | 0.1419 | < 0.0001 | * |
RMTG | 1731 | 0.1858 | 0.1631 | 0.1860 | 0.1309 | 0.7996 | |
LMTG | 1028 | -0.0211 | 0.1868 | 0.0651 | 0.1740 | < 0.0001 | * |
PC | 3929 | 0.8131 | 0.3491 | 0.7818 | 0.3482 | < 0.0001 | * |
Nvoxel = number of voxels in each ROI, mean and standard deviation of β-values before and after Ayahuasca ingestion (in % BOLD signal change). * Indicates significant differences after Ayahuasca (p<0.0011, corresponding to p<0.01 corrected for multiple comparisons by the number of ROI).