Fig 5. A: Similarity Cluster analysis of pA ₂s of the antagonists, derquantel, paraherquamide and methyllycaconitine against the agonists beph (bephenium), trib (tribendimidine), then (thenium), lev (levamisole), pyr (pyrantel), oxa (oxantel), meth (methyridine), nic (nicotine) (ordinate: similarity, averaged, squared Euclidian, standardized variable, estimated using Minitab 13.2 (State College, PA) showing that tribendimidine does not group with levamisole and is closer to bephenium.

B: Schematic illustration of the selectivity of tribendimidine and levamisole for B-subtype (green) and L-subtype (red) nAChRs.