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. 2015 Feb 13;10(2):e0118336. doi: 10.1371/journal.pone.0118336

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© 2015 Ito et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 7 — Src activation represses FAT4 gene expression through the MEK/Erk/Cofilin1 cascade, which induces actin depolymerization in tumor transformation. FAT4 gene repression further elicits YAP/TAZ activation.