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. 2015 Feb 13;10(2):e0117599. doi: 10.1371/journal.pone.0117599

Fig 2. Biliary parameters and bile composition of Cftr knockout mice (Cftr-/-) and controls, fed a control diet or a cholic acid (CA) containing diet for 3 weeks.

Fig 2

Biliary bile flow (A), bile salt concentration (B), bile salt secretion rate (C), phospholipid concentration (D), phospholipid-to-bile salt ratio (E), serum ALT levels (F), percent contribution to total biliary bile salts of cholate, deoxycholate and others (chenodeoxycholate, ursodeoxcholate, α-muricholate and β-muricholate) (G), and, Heuman index of biliary bile salts representing the hydrophobicity (H), in Cftr knockout mice (Cftr -/-) and control littermates (Cftr +/+) after a control or 0.5%-CA (wt/wt) chow diet for three weeks. Data are presented as means ± SEM or percentage (panel G) of N = 5–7 mice per group. *P-value<0.05.