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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Mayo Clin Proc. 2015 Feb;90(2):176–183. doi: 10.1016/j.mayocp.2014.12.009

Table 4.

a Rate Ratio (95% Confidence Interval) of Hospitalization for Specific Disease Categories of Patients with Rheumatoid Arthritis by Select Metrics of Disease Severityb

Disease Categories Total number of hospitalizations RF/ACPA + Erosions Nodules Repeatedly high ESR
Overall 2968 1.04 (0.97, 1.13) 1.24 (1.14, 1.34) 1.01 (0.91, 1.11) 2.76 (2.51, 3.02)
Infectious, Parasitic 65 1.03 (0.62, 1.79) 0.95 (0.50, 1.64) 1.19 (0.58, 2.12) 2.33 (1.10, 4.23)
Neoplasms 149 1.13 (0.81, 1.64) 1.43 (0.99, 2.00) 0.60 (0.33, 0.98) 2.52 (1.59, 3.76)
Endocrine, Metabolic 105 0.85 (0.57, 1.28) 2.01 (1.34, 2.95) 0.37 (0.14, 0.72) 4.75 (3.03, 7.14)
Blood, Blood-Forming Organs 50 2.69 (1.35, 6.67) 1.48 (0.78, 2.61) 0.68 (0.23, 1.45) 0.91 (0.22, 2.20)
Mental 108 0.58 (0.40, 0.85) 0.98 (0.60, 1.50) 1.15 (0.66, 1.83) 5.95 (3.92, 8.78)
Nervous, Sense Organs 81 1.48 (0.92, 2.57) 1.13 (0.66, 1.81) 0.82 (0.39, 1.47) 5.25 (3.18, 8.27)
Circulatory 610 0.80 (0.68, 0.94) 1.21 (1.01, 1.45) 1.08 (0.86, 1.33) 3.15 (2.57, 3.82)
Respiratory 320 1.38 (1.08, 1.80) 0.82 (0.61, 1.07) 1.58 (1.20, 2.04) 4.33 (3.35, 5.52)
Digestive 289 0.97 (0.76, 1.25) 0.85 (0.63, 1.12) 0.66 (0.44, 0.94) 2.29 (1.64, 3.10)
Genitourinary 177 0.67 (0.50, 0.91) 1.13 (0.79, 1.56) 0.65 (0.38, 1.01) 1.78 (1.10, 2.68)
Complications of Pregnancy (females only) 40 0.38 (0.20, 0.80) 0.72 (0.29, 1.48) 1.37 (0.55, 2.80) 1.90 (0.64, 4.14)
Skin, Subcutaneous 77 1.39 (0.86, 2.41) 1.74 (1.06, 2.74) 1.18 (0.61, 2.01) 1.12 (0.42, 2.24)
Musculoskeletal, Connective Tissue 439 1.58 (1.28, 2.00) 1.96 (1.61, 2.37) 1.11 (0.85, 1.41) 1.85 (1.38, 2.41)
Injury, Poisoning 297 1.11 (0.87, 1.44) 1.29 (1.00, 1.66) 1.17 (0.86, 1.56) 2.28 (1.64, 3.07)
Symptoms Ill-Defined 141 1.20 (0.84, 1.76) 1.13 (0.75, 1.62) 1.23 (0.77, 1.84) 2.83 (1.79, 4.21)
a

Statistically significant results are presented in bold font.

b

Results for the following CCS categories were not shown due to fewer than 10 total hospitalizations in the RA cases: congenital anomalies; conditions originating in the perinatal period; residual/unclassified codes.