Table 2.

Variety of methods in current practice to calculate dose of intratracheal recombinant human DNase.

Basis for calculation	Dose
Variable dose based on body surface area	2 mg/m2
Variable dose based on weight	0.2 mg/kg
	0.25 mg/kg
	0.25 mg/kg but only up to a maximum of 5 mg
	0.1 mg/kg if >10 kg or 0.25 mg if <10 kg (diluted)
Fixed dose but diluted to a volume based on weight	2.5 mg diluted in saline to volume of 1 mL/kg
	2.5 mg diluted to either 10 mL or 50 mL (depends on size)