Table 2.

Minor allele frequencies for atrial fibrillation susceptibility loci

		Discovery				Validation
		Total (N=556)	No PoAF (N=391)	PoAF (N=165)	P value	Total (N=1164)	No PoAF (N=828)	PoAF (N=336)	P value	Between cohort P value
Chr. 1q21	rs13376333 (C/T)	30.3%	28%	35.8%	0.04	29.6%	28.7%	31.8%	0.24	0.74
	rs6666258 (G/C)	30.8%	28%	37.3%	0.01	25%	24.2%	27.2%	0.06	<0.001
Chr. 1q24	rs3903239 (G/A)	39.1%	38.7%	40%	0.80	56.8%	57.9%	54.3%	0.14	<0.001
Chr. 4q25	rs2200733 (C/T)	11.1%	10.5%	12.4%	0.62	12.8%	10.7%	17.9%	<0.001	0.25
Chr. 7q31	rs3807989 (G/A)	45.1%	44.2%	47.3%	0.55	41%	41%	41.1%	0.90	0.009
Chr. 9q22	rs10821415 (C/A)	37.2%	36.6%	38.8%	0.80	44.3%	44.3%	44.2%	0.53	0.001
Chr. 10q22	rs10824026 (A/G)	18.8%	19.6%	17%	0.17	15.5%	16.7%	12.6%	0.02	0.05
Chr. 14q23	rs1152591 (G/A)	42.5%	42.7%	42.1%	0.70	47.7%	48.3%	46.3%	0.52	0.02
Chr. 16q22	rs2106261 (G/A)	17.9%	17.8%	18.2%	0.44	14.4%	13.4%	17%	0.04	0.01
	rs7193343 (C/T)	16.5%	16.2%	17%	0.94	15.3%	14.4%	17.6%	0.16	0.57

PoAF: Postoperative atrial fibrillation