Table 1.
Baseline demographics and pERM intensity scores in GCA patients compared with controls
| GCA (n = 36) |
Controls (n = 18) | P-value | Adjusted P-valuea | ||
|---|---|---|---|---|---|
| GCA biopsy positive (n = 19) | GCA biopsy negative (n = 17) | ||||
| Age, mean (s.d.), years | 78.4 (9.2) | 76.6 (7.9) | 78.4 (10.5) | 0.81 | |
| Female, n (%) | 14 (73.7) | 16 (94.1) | 14 (77.8) | 0.2 | |
| Prednisone, mean (s.d.), mg | 55.6 (17.9) | 50.6 (17.1) | 47.2 (27.2) | 0.5 | |
| Hypertension, n (%) | 8 (42.1) | 10 (58.8) | 12 (66.7) | 0.39 | |
| Diabetes mellitus, n (%) | 1 (5.5) | 6 (35.3) | 4 (22.2) | 0.11 | |
| Statin, n (%) | 11 (61.1) | 8 (47.1) | 5 (26.3) | 0.13 | |
| pERM intensity score | 0.0109 | 0.0046 | |||
| Dichotomousb | |||||
| Low, n (%) | 4 (21.1) | 1 (5.9) | 10 (55.6) | ||
| High, n (%) | 15 (78.9) | 16 (94.1) | 8 (44.4) | ||
| pERM intensity score | |||||
| Continuousc | |||||
| Mean (s.d.) | 5.4 (1.06) | 5.6 (0.79) | 4.1 (1.41) | 0.0009 | |
aAdjusted for age, sex, hypertension, diabetes mellitus, and prednisone and statin use. bDichotomous pERM intensity score with low score ≤4 and high score >4. cContinuous pERM intensity score range 0–6. pERM: phosphorylated ezrin/radixin/moesin.