Table 3.
Associations (OR (95%CI)) between tertiles of food groups (servings per day) during the 2nd trimester of pregnancy and unilateral retinoblastoma
| Food group tertiles (servings per day) | Conditional Logistic Model | Unconditional Logistic Modela | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case N |
n=92 matched setsb | n=85 matched setsc | Case N |
Cases: n=183, Controls: n=144 | Cases: n=163, Controls: n=136 | ||||||||||
| Crude OR |
95% C.I. | Adj ORd |
95% C.I. | Crude OR |
95% C.I. | Adj ORd |
95% C.I. | ||||||||
| Fruit | |||||||||||||||
| 0 – 1.37 | 33 | ref | ~ | ~ | ref | ~ | ~ | 75 | ref | ~ | ~ | ref | ~ | ~ | |
| >1.37 – 2.43 | 38 | 1.17 | 0.60 | 2.26 | 0.86 | 0.38 | 1.94 | 65 | 0.87 | 0.51 | 1.47 | 0.84 | 0.46 | 1.54 | |
| >2.43 – 8 | 21 | 0.70 | 0.34 | 1.46 | 0.38 | 0.14 | 1.02 | 43 | 0.60 | 0.35 | 1.05 | 0.56 | 0.28 | 1.12 | |
| Citrus | |||||||||||||||
| 0 – 0.16 | 27 | ref | ~ | ~ | ref | ~ | ~ | 65 | ref | ~ | ~ | ref | ~ | ~ | |
| >0.16 – 0.86 | 44 | 2.17 | 1.04 | 4.51 | 2.23 | 0.94 | 5.29 | 79 | 1.30 | 0.78 | 2.18 | 1.34 | 0.75 | 2.39 | |
| >0.86 – 3.5 | 21 | 1.58 | 0.70 | 3.56 | 1.98 | 0.72 | 5.44 | 39 | 0.78 | 0.44 | 1.39 | 0.76 | 0.39 | 1.50 | |
| Dairy | |||||||||||||||
| 0 – 1.57 | 31 | ref | ~ | ~ | ref | ~ | ~ | 73 | ref | ~ | ~ | ref | ~ | ~ | |
| >1.57 – 2.73 | 34 | 1.06 | 0.52 | 2.15 | 0.61 | 0.25 | 1.52 | 57 | 0.83 | 0.49 | 1.42 | 0.79 | 0.43 | 1.48 | |
| >2.73 – 6.51 | 27 | 0.83 | 0.39 | 1.76 | 0.36 | 0.12 | 1.09 | 53 | 0.78 | 0.46 | 1.35 | 0.62 | 0.30 | 1.27 | |
| Vegetables | |||||||||||||||
| 0.44 – 1.66 | 20 | ref | ~ | ~ | ref | ~ | ~ | 56 | ref | ~ | ~ | ref | ~ | ~ | |
| >1.66 – 2.66 | 41 | 2.03 | 0.96 | 4.27 | 2.39 | 0.93 | 6.19 | 72 | 1.26 | 0.74 | 2.16 | 1.68 | 0.90 | 3.15 | |
| >2.66 – 6.94 | 30 | 1.46 | 0.70 | 3.03 | 1.04 | 0.39 | 2.74 | 54 | 0.97 | 0.56 | 1.69 | 1.07 | 0.54 | 2.12 | |
| Poultry | |||||||||||||||
| 0 – 0.16 | 26 | ref | ~ | ~ | ref | ~ | ~ | 59 | ref | ~ | ~ | ref | ~ | ~ | |
| >0.16 – 0.43 | 32 | 0.91 | 0.42 | 1.93 | 0.92 | 0.36 | 2.38 | 57 | 0.72 | 0.42 | 1.22 | 0.82 | 0.44 | 1.53 | |
| >0.43 – 1.08 | 34 | 1.90 | 0.88 | 4.10 | 2.33 | 0.82 | 6.63 | 67 | 1.62 | 0.91 | 2.87 | 1.71 | 0.86 | 3.40 | |
| Red meat | |||||||||||||||
| 0 – 0.30 | 37 | ref | ~ | ~ | ref | ~ | ~ | 75 | ref | ~ | ~ | ref | ~ | ~ | |
| >0.30 – 0.65 | 31 | 0.58 | 0.27 | 1.23 | 0.53 | 0.22 | 1.30 | 62 | 0.80 | 0.48 | 1.34 | 0.80 | 0.45 | 1.43 | |
| >0.65 – 2.22 | 24 | 0.44 | 0.19 | 1.03 | 0.35 | 0.11 | 1.13 | 46 | 0.78 | 0.45 | 1.37 | 0.68 | 0.35 | 1.33 | |
| Cured meat | |||||||||||||||
| 0 – 0.08 | 31 | ref | ~ | ~ | ref | ~ | ~ | 65 | ref | ~ | ~ | ref | ~ | ~ | |
| >0.08 – 0.16 | 24 | 1.77 | 0.77 | 4.07 | 2.90 | 0.99 | 8.55 | 42 | 1.27 | 0.71 | 2.29 | 1.41 | 0.75 | 2.67 | |
| >0.16 – 1.31 | 37 | 2.83 | 1.24 | 6.44 | 5.07 | 1.63 | 15.70 | 76 | 1.64 | 0.99 | 2.73 | 1.53 | 0.85 | 2.77 | |
| Seafood | |||||||||||||||
| 0 – 0 | 30 | ref | ~ | ~ | ref | ~ | ~ | 58 | ref | ~ | ~ | ref | ~ | ~ | |
| >0 – 0.14 | 27 | 1.48 | 0.71 | 3.09 | 1.44 | 0.60 | 3.45 | 50 | 1.21 | 0.69 | 2.13 | 1.45 | 0.78 | 2.71 | |
| >0.14 – 2.22 | 35 | 1.46 | 0.71 | 2.99 | 2.20 | 0.92 | 5.26 | 75 | 1.65 | 0.97 | 2.79 | 2.03 | 1.12 | 3.69 | |
| Grains | |||||||||||||||
| 0.14 – 1.65 | 33 | ref | ~ | ~ | ref | ~ | ~ | 66 | ref | ~ | ~ | ref | ~ | ~ | |
| >1.65 – 2.37 | 28 | 0.84 | 0.43 | 1.64 | 0.59 | 0.25 | 1.38 | 59 | 0.76 | 0.44 | 1.31 | 0.75 | 0.40 | 1.43 | |
| >2.37 – 6 | 31 | 0.92 | 0.46 | 1.83 | 0.59 | 0.21 | 1.61 | 58 | 0.88 | 0.51 | 1.51 | 0.79 | 0.38 | 1.67 | |
| Sweets | |||||||||||||||
| 0 – 0.88 | 28 | ref | ~ | ~ | ref | ~ | ~ | 52 | ref | ~ | ~ | ref | ~ | ~ | |
| >0.88 – 1.75 | 35 | 1.39 | 0.68 | 2.83 | 1.78 | 0.75 | 4.23 | 67 | 1.31 | 0.76 | 2.26 | 1.50 | 0.81 | 2.78 | |
| >1.75 – 4.58 | 29 | 1.31 | 0.64 | 2.72 | 2.21 | 0.81 | 6.06 | 64 | 1.25 | 0.72 | 2.16 | 1.24 | 0.61 | 2.49 | |
| Fried foods | |||||||||||||||
| 0 – 0.08 | 23 | ref | ~ | ~ | ref | ~ | ~ | 48 | ref | ~ | ~ | ref | ~ | ~ | |
| >0.08 – 0.24 | 29 | 2.86 | 1.28 | 6.39 | 6.34 | 2.14 | 18.83 | 49 | 1.66 | 0.93 | 2.97 | 1.81 | 0.95 | 3.44 | |
| >0.24 – 1.51 | 40 | 2.65 | 1.21 | 5.82 | 4.89 | 1.72 | 13.89 | 86 | 2.41 | 1.42 | 4.11 | 2.01 | 1.08 | 3.76 | |
Adjusted for matching variable age group
Unilateral retinoblastoma cases and cancer-free controls were matched on age group at time of interview (0–1, 2–3, 4–5, 6–7, 8–9, 10–11,12–13 and 14–15 years).
Seven matched sets were dropped due to missing values for one of the adjustment variables.
Adjusted for mother’s race and education, mother smoked month before or during pregnancy, household income, prenatal vitamin use, and total calories per day.