Figure 2.
A: Representative intracellular Ca2+ transients recorded at a slow pacing cycle length (300 ms) and normalized peak-to-peak demonstrate a longer duration (measured at 85% of diastole) in MI compared to sham hearts. Summary data shows that Ca2+ transient durations are significantly prolonged in MI hearts (n=6) compared to shams (n=5). B: Western blots against SERCA2a and actin (loading control) for sham and MI hearts. Summary data shows that across all hearts (n=3 for each) SERCA2a protein expression was unchanged in MI.