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. 2015 Jan 20;33(7):740–748. doi: 10.1200/JCO.2014.57.6801

Table A2.

Interaction Test in Multivariable Mixed-Effects Models

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Interaction Test and PRO Coefficient for Interaction Term 95% CI P
Time-by-treatment
    IES-R 0.009 −0.062 to 0.081 .797
    FACT-G −0.002 −0.080 to 0.076 .964
    HADS-Anxiety −0.006 −0.025 to 0.014 .587
Treatment-by-coping style
    IES-R 2.477 −3.272 to 8.226 .398
    FACT-G −0.139 −6.847 to 6.569 .968
    HADS-Anxiety 0.647 −1.100 to 2.394 .468

NOTE. In addition to treatment, coping style, and time variables, other covariates included in the models were age, sex, Eastern Cooperative Oncology Group performance status, lactate dehydrogenase, Follicular Lymphoma International Prognostic Index score, and modified Ann Arbor stage.

Abbreviations: FACT-G, Functional Assessment of Cancer Therapy–General; HADS, Hospital Anxiety and Depression Scale; IES-R, Impact of Event Scale–Revised; PRO, patient-reported outcome.