Table A3.
Multivariable Mixed-Effects Models for PROs
| PRO and Covariate | Coefficient for Covariates | 95% CI | P |
|---|---|---|---|
| FACT-G | |||
| Treatment | −1.13 | −4.27 to 2.02 | .482 |
| Coping style | 8.86 | 5.48 to 12.24 | < .001 |
| Time | −0.02 | −0.04 to 0.01 | .297 |
| HADS-Anxiety | |||
| Treatment | 0.69 | −0.12 to 1.49 | .095 |
| Coping style | −2.26 | −3.12 to −1.39 | < .001 |
| Time | −0.01 | −0.02 to 0.00 | .007 |
| IES-R | |||
| Treatment | 0.39 | −2.29 to 3.08 | .774 |
| Coping style | −8.25 | −11.13 to −5.37 | < .001 |
| Time | −0.08 | −0.11 to −0.05 | < .001 |
NOTE. In addition to treatment, coping style, and time variables, other covariates included in the models were age, sex, Eastern Cooperative Oncology Group performance status, lactate dehydrogenase, Follicular Lymphoma International Prognostic Index score, and modified Ann Arbor stage.
Abbreviations: FACT-G, Functional Assessment of Cancer Therapy–General; HADS, Hospital Anxiety and Depression Scale; IES-R, Impact of Event Scale–Revised; PRO, patient-reported outcome.