Table 2.
Induced THP-1 pathways upon M. bovis BCG infection
| Pathway name | Number of genes annotated in pathway | Number of induced genes | P-value |
|---|---|---|---|
| IFN-α/β signaling | 36 | 23 | <1.0 × 10−5 |
| IFN-γ signaling | 28 | 16 | <1.0 × 10−5 |
| RIG-I/MDA5-mediated induction of IFN-α/β pathways | 12 | 8 | <1.0 × 10−5 |
| Cytosolic DNA-sensing pathway | 23 | 8 | 0.00018 |
| Cholesterol biosynthesis | 14 | 6 | 0.0033 |
| Hepatitis C | 71 | 14 | 0.00073 |
| Staphylococcus aureus infection | 11 | 5 | 0.00078 |
| Steroid biosynthesis | 11 | 5 | 0.00078 |
| Iron uptake and transport | 7 | 4 | 0.00096 |
| Toxoplasmosis | 60 | 12 | 0.00152 |
The ten most significantly induced pathways are shown.