Prevalence of K13 mutations and association with parasite clearance half-life. A, Parasite clearance half-life for parasites with K13 mutations (colors) or wild-type alleles (green). Parasites with wild-type alleles are grouped by country (LAO = Laos, BGD = Bangladesh, MMR = Myanmar, VNM = Vietnam, KHM = Cambodia), and parasites with K13 mutations are designated by symbols (Laos = circles, Bangladesh = squares, Myanmar = triangle, Vietnam = inverted triangle, and Cambodia = diamond). Horizontal lines represent median half-lives and 95% confidence intervals for wild-type and K13 mutants represented more than twice in the data set. B, Prevalence of parasites with K13 mutations, by country.