TABLE 2. NOAELs, LOAELs, ED₂₀s, ED₅₀s, and ED₈₀s for Oral Emetic Effects of DON and Its Conjugates D3G, EN139528, and EN139544.

	(μg/kg BW)
Toxin	NOAELa	LOAELb	ED20c	ED50d	ED80e
DON	0.01	0.05	0.02 (0–0.03)	0.03 (0–0.05)	0.04 (0.01–1.1)
D3G	1	2	0.96 (0–0)	1.63 (0–0)	2.78 (0–0)
EN139528	0.25	0.5	0.29 (0–0.41)	0.37 (0.05–0.73)	0.46 (0.32–40.37)
EN139544	1	2.5	1.74 (0.05–2.96)	2.76 (0.73—6.03)	4.39 (2.51–48.53)

^aNOAEL = no observed adverse effect level.

^bLOAEL = lowest observed adverse effect level.

^cED₂₀ = dose causing emesis in 20% of the animals tested.

^dED₅₀ = dose causing emesis in 50% of the animals tested.

^eED₈₀ = dose causing emesis in 80% of the animals tested. ED₂₀, ED₅₀, and ED₈₀ values were determined using a Proc Probit model.