Table 2.
Estimated total and excess cancer cases among people living with HIV in the United States in 2010, by cancer type
| Cancer type | Estimated cases* | Percentage excess or deficit† (95% CI) | Percentage of total excess‡ (95% CI) | ||
|---|---|---|---|---|---|
| Total No. (95% CI) | Expected No. | Excess or deficit No. (95% CI) | |||
| AIDS-defining cancers | 2640 (2400 to 2890) | 230 | 2410 (2170 to 2660) | 91 (90 to 92) | 54 (49 to 58) |
| Non-Hodgkin’s lymphoma§ | 1650 (1470 to 1840) | 200 | 1440 (1270 to 1630) | 88 (86 to 89) | 32 (28 to 36) |
| Kaposi’s sarcoma | 910 (780 to 1060) | 2 | 910 (780 to 1060) | 100 (100 to 100) | 20 (18 to 23) |
| Cervix | 80 (50 to 120) | 30 | 50 (20 to 90) | 66 (46 to 78) | 1 (0 to 2) |
| Non–AIDS defining cancers | 5130 (4780 to 5580) | 3620 | 1510 (1170 to 1960) | 29 (24 to 35) | 46 (42 to 51) |
| Lung | 840 (710 to 1000) | 400 | 440 (300 to 600) | 52 (43 to 60) | 10 (7 to 13) |
| Anus | 760 (630 to 930) | 20 | 740 (610 to 910) | 97 (97 to 98) | 17 (14 to 19) |
| Prostate | 570 (450 to 720) | 970 | -390 (-520 to -250) | -41 (-53 to -26) | 0 (0 to 0) |
| Liver | 390 (300 to 500) | 110 | 280 (200 to 390) | 73 (65 to 79) | 6 (4 to 9) |
| Colorectum | 360 (270 to 470) | 380 | -20 (-110 to 90) | -6 (-28 to 20) | 0 (0 to 2) |
| Hodgkin’s lymphoma | 320 (240 to 420) | 30 | 290 (210 to 390) | 91 (88 to 93) | 6 (5 to 9) |
| Oral cavity and pharynx | 280 (210 to 380) | 140 | 140 (70 to 240) | 51 (34 to 64) | 3 (2 to 5) |
| Female breast | 180 (120 to 260) | 300 | -130 (-190 to -40) | -42 (-61 to -14) | 0 (0 to 0) |
| Miscellaneous | 1430 (1270 to 1620) | 1270 | 160 (-9 to 350) | 11 (-1 to 22) | 4 (0 to 8) |
| All cancers (total) | 7760 (7330 to 8320) | 3850 | 3920 (3480 to 4470) || | 50 (48 to 54) | 100 |
* Cancer cases are rounded to the nearest ten and may not always sum exactly.
† The percentage excess is calculated as excess/total; the percentage deficit is calculated as deficit/expected (see Methods).
‡ This calculation is restricted to the cancers that were present in excess. Deficit cancers were therefore set equal to zero, giving a denominator of 4460 cancer cases for the point estimates. For the groups of AIDS-defining and non–AIDS defining cancers, percentages are calculated as the sum of the percentages for individual cancer sites.
§ Only certain subtypes of non-Hodgkin’s lymphoma (NHL) are AIDS defining, but we grouped all NHLs together, as most cases among HIV-infected people are the AIDS-defining subtypes (40).
|| The excess displayed for all cancers is the net excess. Disregarding cancers occurring in deficit, the total excess is 4460 cancers.