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. 2015 Feb 15;13:52. doi: 10.1186/s12957-015-0465-1

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© Yu et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effects of SDF-1 on the proliferation of osteosarcoma cell lines. (A) SDF-1 promotes the proliferation of osteosarcoma cells in a dose-dependent manner. (B) AMD3100 partially blocks SDF-1-mediated proliferation. (C) AMD3100 downregulates the effects of BMSCs on osteosarcoma cell line proliferation.