Table 5.

Results of docking studies for reported pyrazole-4-carboxylic acid molecules and their binding interactions with residues within 3 Å radius.

Reference compound	Number of hydrogen bonds	Hydrogen bond distance	Functional group of compounds	Functional group of amino acids	Residue number
R4	1	2.280	–N	–OH	Ser289
R5	1	2.639	–C=O	–OH	Ser289
R6	1	2.659	–CN	–NH	Ser342
R7	1	2.138	–O–CH3	–OH	Tyr473
R8	1	2.824	–OH	–C=O	Leu340
R9	2	2.606	–OH	–O–C=O	Glu291
		2.067	–NH	–C=O	Gln271
R10	1	2.324	–C=O	–OH	Ser289