Table 7.
H-bonding interactions and G-score results of docking studies of designed molecules.
Compound | H-bond | Number of H-bonds | G-score | |
---|---|---|---|---|
Amino acid | Distance (Å) | |||
1 | Ser342 | 2.019 | 2 | −8.04 |
Glu343 | 2.126 | |||
3 | His446 | 2.233 | 1 | −7.23 |
4 | Ser342 | 2.489 | 1 | −7.29 |
5 | Met364 | 2.962 | 1 | −8.02 |
6 | Ser342 | 2.047 | 2 | −7.25 |
Glu343 | 2.175 | |||
Rosiglitazone | Ser342 | 2.827 | 1 | −9.94 |