Table 8.
Biological evaluation of compounds on Wistar rats.
Drug | Blood glucose level mg/dL (mean ± SE) | |||
---|---|---|---|---|
0 hr | 1 hr | 3 hr | 6 hr | |
Normal | 90.667 ± 1.585 | 90.667 ± 1.585 | 92.00 ± 1.438 | 91.500 ± 1.996 |
1 | 201.333 ± 4.379 | 137.333 ± 2.963 | 123.667 ± 3.461 | 112.833 ± 4.909 |
2 (CID 20269015) | 201.833 ± 4.778 | 167.833 ± 3.468 | 151.00 ± 2.098 | 139.833 ± 2.358 |
3 | 198.333 ± 9.584 | 155.167 ± 3.321 | 136.833 ± 2.197 | 125.00 ± 4.139 |
4 | 198.667 ± 2.629 | 151.500 ± 1.648 | 125.833 ± 1.887 | 107.333 ± 3.658 |
5 | 190.00 ± 5.471 | 226.667 ± 28.273 | 215.167 ± 10.150 | 210.00 ± 3.873 |
6 | 200.00 ± 7.038 | 204.667 ± 7.292 | 225.333 ± 5.719 | 235.833 ± 4.527 |
Diabetic control | 206.167 ± 5.747 | 210.667 ± 4.364 | 212.00 ± 4.494 | 229.667 ± 5.942 |
Metformin | 201.167 ± 2.120 | 127.333 ± 3.621 | 114.833 ± 3.219 | 110.500 ± 1.607 |