Fig 3. p53 protein levels in tumors of each genotype.
(A) Western blot analysis of p53 using an antibody that detects both wild-type and mutant p53 (CM5). From left to right: 3 MMTV-Hras/p53 +/+, 3 MMTV-Hras/p53 -/-, and 4 MMTV-Hras/p53 R172H/R172H tumors. (B) Immunohistochemical staining with the CM5 anti-p53 antibody in a representative tumor of each of the three genotypes.