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. 2015 Feb 19;10(2):e0118600. doi: 10.1371/journal.pone.0118600

Fig 4. Treatment of amastigote-bearing astrocytes with IFNγ enhances parasite growth.

Fig 4

(A) Primary astrocyte cell cultures were infected by T. cruzi (MOI 1:1) for 4 hours. Afterwards, parasites were washed out, culture medium was replaced and cells were incubated for an additional 20 hours. Amastigote-bearing astrocytes were treated or not with IFNγ (10 ng/mL) and analyzed 24 hours later (48 hours post-infection, p.i.). (B) The graph shows the frequencies of T. cruzi-infected cells bearing different classes of parasite load. Data are presented as mean ± SEM of triplicates. *, p < 0.05 comparing not-treated (NT) with IFNγ-treated astrocytes.