Table 1. In vitro binding affinity of Tfab and Tmab.

	Tfab	Tmab
EC50 rHER2 (nM)	0.1	0.1
IC50 rHER2* (nM)	12	N/A
kon (M-1s-1)	1.42E+05 ± 500	3.03E+05 ± 1000
koff (s-1)	2.64E-05 ± 2E-06	3.03E-04 ± 2. E-06
KD (nM)	0.19 ± 0.01	1.00 ± 0.01

*IC₅₀ values reflect concentration of Tfab required to compete 50% of saturating Tmab IgG.

Errors are standard deviations from technical triplicates.