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. 2015 Feb 19;11(2):e1004649. doi: 10.1371/journal.ppat.1004649

Fig 4. PTX3 modulates expression kinetics of pro-inflammatory mediators during RRV infection in mice.

Fig 4

21-day-old C57BL/6 WT and PTX3-/- (n = 4–7 per group) mice were infected subcutaneously with 104 PFU RRV. Transcriptional profiles of immune mediators, (A) IFN-Ɣ, (B) TNF-α, (C) IL-6 and (D) iNOS were determined by qRT-PCR in the quadriceps at early RRV disease (2 dpi) and peak RRV disease (10 dpi). Data were normalized to HPRT and shown as fold expression relative to WT. Data are presented as mean ± SEM. *P < 0.05, ***P < 0.001, Student unpaired t-test.