Table 5.
Determination of NLX using AuNPs-luminol-potassium ferricyanide SIA-injection CL detection in pure samples and dosage forms in comparison with reported method [3]
| Pure samples | Narcan® ampoules | Reported method [ 3 ] | ||||||
|---|---|---|---|---|---|---|---|---|
| Taken-log conc. | Found-log conc. | Recovery % | Taken-log conc. | Found-log conc. | Recovery % | Taken-log conc. | Found-log conc. | Recovery % |
| 9.0 | 8.99 | 99.9 | 9.0 | 9.00 | 100.0 | 5.0 | 4.96 | 99.2 |
| 8.0 | 7.98 | 99.8 | 8.0 | 7.88 | 98.5 | 4.7 | 4.66 | 99.1 |
| 7.0 | 6.99 | 99.9 | 7.0 | 6.99 | 99.9 | 4.5 | 4.45 | 98.9 |
| 6.0 | 5.96 | 99.3 | 6.0 | 5.95 | 99.2 | 3.9 | 3.89 | 99.7 |
| 5.0 | 4.99 | 99.8 | 5.0 | 4.99 | 99.8 | 3.6 | 3.56 | 98.9 |
| 4.0 | 3.95 | 98.8 | 4.0 | 3.99 | 99.8 | 3.3 | 3.31 | 100.3 |
| 3.0 | 2.98 | 99.3 | 3.0 | 2.98 | 99.3 | |||
| 2.0 | 2.00 | 100.0 | ||||||
| Mean %±SD | 99.6±0.4 | 99.5±0.5 | 99.4±0.6 | |||||
| n | 8 | 7 | 6 | |||||
| Variance | 0.16 | 0.25 | 0.36 | |||||
| % SE* | 0.14 | 0.09 | 0.24 | |||||
| % RSD | 0.40 | 0.50 | 0.60 | |||||
| t-test | 0.72(2.179)** | 0.39(2.201)** | ||||||
| F-test | 2.25(4.15)** | 1.44(4.21)** | ||||||
*% SE= SD/√n; **Figures in parentheses are the tabulated values of t-and F-testes at 95% confidence limit [20].