FIGURE 10.

PDGF (a SOCE channel activator) causes nuclear translocation of ectopically expressed NFAT-GFP at 10 and 20 min poststimulation (A), whereas thrombin (an LRC channel activator) fails to cause NFAT-GFP translocation (B). Blots representing cell cross-sections of fluorescence intensity (diagonal white bars) at 0 and 20 min and quantification of data at 0-, 10-, and 20-min (′) time points from four independent experiments per condition are shown. Scale bars, 10 μm. Error bars represent S.E. AFU, arbitrary fluorescence units.