FIGURE 10.

Surface binding of ICs to CD4⁺ T cells from two different mouse models of autoimmunity. A, increased ICs binding to CD4⁺ T-cells from KRN mice crossed to NOD mice (K/BxN), a well-established mouse model of autoimmune arthritis, but not to CD4⁺ T-cells from control KRN mice. Data is representative of an analysis that included 6 mice per group. B, ICs binding to CD4⁺ T-cells from TxA23 mice, a well-established mouse model of Autoimmune Gastritis, but not to CD4⁺ T-cells from control (BALB/c) mice. Data are representative of an analysis that included 5 mice per group.