Figure 1.

mRNA and protein expression levels of CK1δ in various established malignant lymphoma cell lines. The expression levels of CK1δ in various established malignant lymphoma cell lines were analyzed by quantitative RT-PCR (A) and quantitative Western blot analyses (B). Black dots represent gene or protein expression of one cell line relative to tonsil reference material. For clear presentation cell lines were assigned to their entity of lymphoma. Each black dot of gene expression analysis is representative for three replicates. Error bars indicate the fold-change range for the calculated ΔΔCt values. For quantitative Western blot analyses data from one representative analysis out of three are shown. In case more than one cell line per lymphoma entity was tested, mean values are indicated by a black cross. Abbreviations: CK1δ: Casein Kinase 1 isoform delta, cHL: classical Hodgkin lymphoma including HDLM2, KM-H2, L-1236, L-428, L-540, and U-H01 cells, NLPHL: nodular lymphocyte predominant Hodgkin lymphoma represented by DEV cells, DLBCL: diffuse large B cell lymphoma containing DOHH-2, SU-DHL-6, and SU-DHL-8 cells, PMBL: primary mediastinal large B cell lymphoma including KARPAS-1106P and MedB-1 cells, BL: Burkitt lymphoma including DAUDI, JIYOYE, RAJI, and RAMOS cells, B-ALL: B cell acute lymphoblastic lymphoma represented by NALM-6 cells, T-ALL: T cell acute lymphoblastic lymphoma represented by JURKAT cells.