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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Cell Metab. 2014 Jun 19;20(1):85–102. doi: 10.1016/j.cmet.2014.05.011

Fig. 3. Hepatic TCPTP deletion promotes obesity and insulin resistance.

Fig. 3

7 week-old lox/lox and LTKO mice were HFF for 12 weeks and (a, e) body weights, (b, f) gross morphology, (c, g) tissue weights, (d, h) body composition and (i) oxygen consumption, RER, energy expenditure and ambulatory activity assessed. (j) 7 week-old lox/+ and LTKO HET mice were HFF for 20 weeks and body weights and composition determined. (k) HFF mice were subjected to insulin tolerance tests and (l) fed and fasted blood glucose levels and plasma insulin levels determined. (m) Fasted HFF mice were injected with insulin and livers extracted for immunoblot analysis. Representative and quantified (means ± SEM) results are shown.

HHS Vulnerability Disclosure