Figure 1.

NPC structure and molecular composition. Representation and predicted molecular composition of the vertebrate NPC. For the corresponding orthologs in other model organisms, see Rothballer and Kutay (2012). The NPC core scaffold and its components are represented in dark blue and light blue, the transmembrane subunits are shown in green, the cytoplasmic structures are represented in magenta, and the basket is shown in orange. Peripheral Nups showing higher mobility by FRAP, and other approaches are depicted in black.