Table 3.

Incremental Cost-Effectiveness.^*

Strategy	Cost	Life Expectancy	QALE	Incremental Costs†	Incremental Life Expectancy	Incremental QALE	Cost per Life-Yr	Cost per QALY
	U.S. $	life-yr	QALY	U.S. $	life-yr	QALY	U.S. $ (95% CI)
CT screening	3,074	14.7386	10.9692	1,631	0.0316	0.0201	52,000 (34,000–106,000)	81,000 (52,000–186,000)
Radiographic screening	1,911	14.7071	10.9491	469	0	0	NA	NA
No screening‡	1,443	14.7071	10.9491	—	—	—	—	—

^*All costs were calculated for the base case, which reflects several assumptions made to reduce the complexity of the analysis and minimize the use of variables for which there are no reliable estimates. NA denotes not applicable, QALE quality-adjusted life expectancy, and QALY quality-adjusted life-year.

^†Incremental costs are in reference to the strategy of no screening because the radiography strategy cost more but provided no incremental health benefit as compared with no screening.

^‡The cost of the strategy of no screening included the cost of the diagnosis and treatment of lung cancer without low-dose CT or radiographic screening.