Skip to main content
. 2014 Aug 15;29(1):11–19. doi: 10.1038/leu.2014.222

Figure 2.

Figure 2

Chemical and X-ray structure of volasertib. Chemical structure (a) and binding mode (b) of volasertib in the adenosine triphosphate-binding pocket of human Plk1. Reprinted from Clinical Cancer Research, Copyright 2009, 15/9, 3094–3102, Rudolph et al.19 ‘BI 6727, a Polo-like kinase inhibitor with improved pharmacokinetic profile and broad antitumor activity', with permission from AACR.