Table 4.
Prediction of variable in study for the risk of developing DR in T2DM patients by multiple regression analysis
| Variables | T2DM patients without DR (DNR) | T2DM patients with DR | t-statistics value (t) | P value |
|---|---|---|---|---|
| N (%) | N (%) | |||
| Age (mean ± SD) | 55.64 ± 10.23 | 57.86 ± 8.67 | 0.29 | 0.776 |
| Gender (Males vs Females) | 58 (36.3%)/102 (63.8%) | 36 (46.2%)/42 (53.8%) | 1.13 | 0.262 |
| BMI (mean ± SD) | 34.08 ± 6.99 | 33.92 ± 6.53 | −0.463 | 0.644 |
| Creatinine level (micromole/lit) ± SD | 69.30 ± 28.55 | 81.5 ± 45.27 | 1.82 | 0.070 |
| Glycated hemoglobin (HbA1c) mean% ± SD | 8.24 ± 1.72 | 8.82 ± 1.83 | 1.99 | 0.048 |
| LDL(mmol/lit)mean ± SD | 2.95 ± 0.94 | 2.68 ± 1.04 | −2.22 | 0.028 |
| Triglycerides (mmol/lit) mean ± SD | 1.77 ± 1.23 | 1.62 ± 0.75 | −1.07 | 0.286 |
| Blood Urea Nitrogen (mmol/lit) mean ± SD | 5.24 ± 2.54 | 6.97 ± 4.49 | −0.944 | 0.347 |
| Mean Glucose levels (mmole/lit) ± SD | 10.55 ± 6.68 | 9.92 ± 4.23 | −0.165 | 0.87 |
| SLMAP rs17058639 C > T genotypes | TT = 29 (18.1%) | TT = 6 (7.7%) | −2.15 | 0.033 |
| CT = 71 (44.4%) | CT = 30 (38.5%) | |||
| CC = 60 (37.5%) | CC = 42 (53.8%) | |||
| SLMAP rs1043045 C > T | CC = 31 (19.4%) | CC = 9 (11.5%) | 0.95 | 0.294 |
| CT = 70 (43.8%) | CT = 31 (39.7%) | |||
| TT = 59 (36.9%) | TT = 38 (48.7%) | |||
| SLMAP rs1057719 A > G | GG = 30 (18.8%) | GG = 8 (10.3%) | 0.10 | 0.319 |
| AG = 71 (44.4%) | AG = 32 (41.0%) | |||
| AA = 59 (36.9%) | AA = 38 (48.7%) |
t= > +2 or < −2 depicts significance in data; significant values shown in bold.