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. 2014 Sep 19;5:30. doi: 10.1186/2041-9139-5-30

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Copyright © 2014 Layden and Martindale; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Nvdelta activates Nvnotch activity to suppress NvashA. (A-B) Shown are Aboral views of NvashA expression in control (A) and Nvdelta overexpressing (OE) (B) animals. Phenotypic classes were scored as no expression, weak, wild-type (WT) levels, and strong expression. The key is shown in the image and bars at the base of each image represent the percentage of animals in each phenotypic class. (C) Relative fold change of NvashA and previously identified Nvasha neural gene targets and in animals overexpressing Nvdelta (light grey bars) and animals that are overexpressing Nvdelta and treated with DAPT (dark grey bars). Red rectangle denotes relative fold change −1.5 to 1.5, which corresponds to no change in relative expression.