Figure 5. The disease course in naive or primed (with H1N1 or H9N2 IAVs 10–12 weeks previously) mice following challenge with the H7N9 virus.

The mice were challenged with 10^4.5 TCID₅₀ H7N9 virus (10 MLD₅₀). (A) The survival ratio and (B) weight loss during the disease course. Data represent mean ± SEM, n = 8–10/group from two independent experiments. (A) * p<0.05, log-rank test, naive versus other four primed groups. (B) * p<0.05, t test, naïve versus the every other four primed groups; # p<0.05, t test, Ck/HK/TP38 versus the every other three primed groups.