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. 2014 Dec 23;15:585. doi: 10.1186/s12865-014-0063-y

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© Marioli et al.; licensee BioMed Central. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Expression of TREM-1 on monocytes A) gating on monocytes; B) negative isotype anti-IgG1-PE control; C) staining with anti-TREM-1-PE; D) % expression of TREM-1 on monocytes of healthy volunteers (n = 10), of patients with sepsis (n = 41), of patients with severe sepsis (n = 25) and of patients with septic shock (n = 9); E) fluoresecence of TREM-1 on monocytes of healthy volunteers (n = 10), of patients with sepsis (n = 41), of patients with severe sepsis (n = 25) and of patients with septic shock (n = 9); F) relative transcripts of TREM-1 in the cytoplasm monocytes of patients with sepsis (n = 12), of patients with severe sepsis (n = 20) and of patients with septic shock (n = 6); and G) circulating sTREM-1 of healthy volunteers (n = 10), of patients with sepsis (n = 41), of patients with severe sepsis (n = 25) and of patients with septic shock (n = 9). Asterisks denote statistical significant differences compared to healthy volunteers.