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. 2015 Jan 20;12:4. doi: 10.1186/s12950-015-0049-4

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© Kapewangolo et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Antioxidant effect of the O. labiatum extract (squares) and the isolated compound (triangles). The DPPH free radical scavenging, the FRAP, cupric ion reducing activity, and crocin bleaching effect are shown in A, B, C and D respectively (n = 5-6.). The DPPH data is shown as percentage inhibition. The IC_50s for the extract were 13 ± 0.8 μg/mL, 53.62 ± 0.57, 47.32 ± 0.76 μg/mL and 54.86 ± 1.28 μg/mL respectively. Ascorbic acid was used as positive control. The extract exhibited strong antioxidant activity while the diterpenoid compound did not. *tested in two fold serial dilutions from 0.08-10 μg/mL.