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. 2015 Jan 20;12:4. doi: 10.1186/s12950-015-0049-4

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© Kapewangolo et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Influence of labda-8(17),12 E ,14-triene-2R,18-diol on cytokine production in PBMCs as quantitated by CBA analysis and flow cytometry. Cells were treated with a non-toxic concentration of 50 μM. Concentrations obtained of tested cytokines were log transformed in order to make the data comparable. Control treatments are unshaded whereas compound treated cells are shaded. IL-6 was the only cytokine that was up-regulated by the compound. The rest of the cytokines were significantly (*p < 0.05) down-regulated.