Table 2.

Two regions with trans-species polymorphisms shared between humans and chimpanzees

		Expected length of the		Number of shared
Region (the nearest gene)	Observed length of the regiona, b	ancestral segment (upper 95% quantile)	Number of all shared SNPs (number of shared SNPs at non-CpG sites)b	SNPs in other primate speciecsc	LD pattern among shared SNPs
FREM3	6.7 kb	263 bp	13	3	In almost perfect LD
		(800 bp)	(13)	(Among both 31 gorillas	with the same alleles
				and 10 orangutans)	coupled in both species
IGFBP7	870 bp	263 bp	5	1	Within cluster 1 or 2: in
(clusters 1 and 2)		(800 bp)	(2)	(Among both 31 gorillas	almost perfect LD with
				and 10 orangutans)	the same alleles coupled
					in both species
					Between clusters 1 and 2: in strong LD with the opposite phases (i.e., with different alleles coupled) in the two species
IGFBP7	200 bp	263 bp	3	None	Within cluster 3: in almost
(cluster 3)		(800 bp)	(1)		perfect LD with the same
					alleles coupled in both species
					With clusters 1 and 2: in strong LD in chimpanzees but not in LD in humans

^aThe span of the region is defined as the distance between the two outermost shared SNPs that are in significant LD in both species.

^bData are from Leffler et al. (2013).

^cData are from Great Ape Genome Project (Prado-Martinez et al. 2013).