. 2015 Feb 13;11:229–235. doi: 10.2147/TCRM.S73827

Table 2.

Univariate and multivariate analyses of variables to identify independent factors for screening for no or insignificant fibrosis

Variable	No or insignificant fibrosis (n=109)	Significant fibrosis or cirrhosis (n=20)	P-value
Variable	No or insignificant fibrosis (n=109)	Significant fibrosis or cirrhosis (n=20)	Univariate analysis	Multivariate analysis
Age (years), mean ± SD	32.6±6.7	31.1±6.2	0.772	0.201
Male, n (%)	65 (64.4%)	20 (76.9%)	0.065	0.269
Genotype B, n (%)	68 (67.3%)	22 (84.6%)	0.802	0.912
ALT (IU/L), mean ± SD	33.5±17.7	26.5±17.1	0.107	0.761
LSM (kPa), mean ± SD	6.1±2.0	11.7±3.4	<0.001	<0.001
Log₁₀ HBV DNA (copies/mL), mean ± SD	7.4±1.2	7.7±1.0	0.981	0.674
Log₁₀ HBsAg (IU/mL), mean ± SD	4.4±0.8	3.5±1.2	<0.001	0.045

Abbreviations: ALT, alanine aminotransferase; DNA, deoxyribonucleic acid; HBsAg, hepatitis B surface antigen; HBV, hepatitis B virus; LSM, liver stiffness measurement; SD, standard deviation.