Table 1.
Physiological data
| Control (n=7) |
DM (n=7) |
DM + ARB (n=7) |
|
|---|---|---|---|
| Body weight (g) | 251±4 | 203±8‡ | 211±9† |
| Systolic blood pressure (mmHg) | 97±7 | 113±5 | 85±6§ |
| Urinary protein (mg/day) | 4.4±1.1 | 14.3±2.6† | 6.5±0.5§ |
| Creatinine clearance (mL/min/100 g body weight) | 0.83±0.06 | 2.59±0.55* | 1.74±0.23 |
| HbA1c (%) | 3.4±0.1 | 9.0±0.3‡ | 8.7±0.3‡ |
| Insulin (ng/mL) | 1.63±0.90 | 0.13±0.03 | 0.16±0.03 |
Notes:
*
P<0.05
†
P<0.01
‡
P<0.001 versus control
§
P<0.05 versus DM.
Abbreviations: ARB, angiotensin receptor blocker; HbA1c, glycated hemoglobin; DM, diabetes mellitus.