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IC50 values of DOX in free or micelle form
| Cells | DOX (μM) | P407-TPGS-DOX (μM) | FA-P407-TPGS-DOX (μM) |
|---|---|---|---|
| SKOV3 | 7.7±0.4 | 4.8±0.5 | 3.6±0.4 |
| SKOV3-DOX | 17.5±1.3 | 6.1±0.7 | 5.7±0.8 |
Abbreviations: DOX, doxorubicin; P407, poloxamer 407; TPGS, D-α-tocopheryl polyethylene glycol succinate; FA, folic acid; SKOV3-DOX, DOX-resistant SKOV3.
