Table 2.
Summary of characteristics of studies
| Characteristic | Number of studies | % of studies | % of subjects |
|---|---|---|---|
| Stroke patients | 14 | 45 | 37 |
| Non stroke | 17 | 55 | 63 |
| Studies of stroke patients | % of studies of stroke patients | % of stroke patients | |
| Recorded stroke sub-type | 13 | 87 | 88 |
| Inpatients and outpatients | 1 | 7 | 1.2 |
| Inpatients only | 12 | 80 | 96 |
| USA | 3 | 20 | 22 |
| Europe | 5 | 33 | 48 |
| Asia | 7 | 47 | 29 |
| Studies of subtyped stroke patients | % of studies that subtyped stroke | % of patients with subtyped stroke | |
| OCSP | 1 | 8 | 7 |
| TOAST | 12 | 92 | 93 |
| CT Imaging | 4 | 31 | 40 |
| MRI | 2 | 15 | 12 |
| CT and MRI | 4 | 31 | 17 |
| Measured proteinuria | 4 | 31 | 9 |
| Measured eGFR | 9 | 69 | 69 |
| Patients that developed acute kidney injury | 1 | 8 | 26 |
| Studies of imaging features of SVD patients | % of studies of imaging features of SVD | % of subjects in the studies of imaging features of SVD | |
| Healthy volunteers | 8 | 47 | 57 |
| Diabetic patients | 4 | 24 | 10 |
| Any vascular risk factor | 2 | 12 | 4 |
| Hypertensive patients | 1 | 6 | 0.2 |
| Hypertensive patients and their siblings | 1 | 6 | 11 |
| Excluded previous stroke | 10 | 59 | 84 |
| Excluded severe renal impairment | 9 | 53 | 35 |
| 1.5T | 14 | 82 | 86 |
| 0.5T | 3 | 18 | 14 |
| Fazekas or similar | 5 | 29 | 24 |
| Count of silent brain infarcts | 6 | 35 | 52 |
| Automated measure of the volume of WMH | 5 | 29 | 24 |
| Images analysed by a blinded observer | 9 | 53 | 46 |
| Measured eGFR | 8 | 47 | 70 |
| Measured proteinuria | 5 | 29 | 13 |
| Measured both | 3 | 18 | 14 |
| Measured serum creatinine | 1 | 6 | 2 |
| Multivariate analysis | 13 | 76 | 81 |