Table 1.

Acute FSS decreases circulating 3α,5α-THP and corticosterone levels in C57BL/6J mice

	Pregnenolone	3α,5α-THP	Corticosterone
	Test	Test	Basal	Test
No stress	111.5±9.3	1,034.0±79.6	76.4±16.2	271.1±46.2+
Stress	140.7±11.8	607.6±75.1*	81.6±14.7	493.2±43.3**#

Data are presented as picograms per milliliter for pregnenolone and 3α,5α-THP and nanograms per milliliter for corticosterone in nonstressed and stressed mice (n=12–15).

^*p<0.001 (compared to nonstressed controls);

^**p<0.0001 (compared to nonstressed controls);

⁺p<0.01 (compared to basal levels);

^#p<0.0001 (compared to basal levels)