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. Author manuscript; available in PMC: 2015 Feb 20.

Published in final edited form as: Alcohol Clin Exp Res. 2012 Jun 4;36(12):2157–2167. doi: 10.1111/j.1530-0277.2012.01845.x

Fig. 4 — Rolipram selectively decreased ethanol consumption for 5 consecutive hours in FH/Wjd rats having continuous access to 5% ethanol. Rolipram (0.1, 0.2 mg/kg, s.c.) was administered 30 min before the start of the drinking session; it significantly decreased ethanol consumption for 2h (at 0.1 mg/kg) or 5h (at 0.2 mg/kg) after the onset of drinking (A), but had no effect on water intake (B). The values are expressed as mean consumption (g/kg) of ethanol or water ± SEM (two-way repeated measures ANOVA followed by Bonferroni post hoc test). *, p < 0.05; **, p < 0.01; ***, p < 0.001 compared with NS (0 mg/kg rolipram); n = 6.

Fig. 4 — Rolipram selectively decreased ethanol consumption for 5 consecutive hours in FH/Wjd rats having continuous access to 5% ethanol. Rolipram (0.1, 0.2 mg/kg, s.c.) was administered 30 min before the start of the drinking session; it significantly decreased ethanol consumption for 2h (at 0.1 mg/kg) or 5h (at 0.2 mg/kg) after the onset of drinking (A), but had no effect on water intake (B). The values are expressed as mean consumption (g/kg) of ethanol or water ± SEM (two-way repeated measures ANOVA followed by Bonferroni post hoc test). *, p < 0.05; **, p < 0.01; ***, p < 0.001 compared with NS (0 mg/kg rolipram); n = 6.