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. 2015 Feb 13;15:141. doi: 10.1186/s12889-015-1480-4

Table 1.

Pre and post intervention values for specific model parameters

Intervention (all public sector unless otherwise specified) Model parameters influenced Pre-intervention value Notes and reference for pre intervention Post-intervention value Notes and Reference for post intervention
Community Education Patient delay (probability of seeking care with a 1 year delay) 41 · 79 days = 0 · 11 probability of a 1 year delay [14-17] 21 days = 0 · 06 probability of a 1 year delay Assume 50% reduction in delay days
DOTS expansion for diagnosis Incorrect diagnostic test ordered by heath professional 0 · 603 [18] 0 · 351 [19]
Diagnostic delay (probability of incurring a 1 year delay) 29 · 49 days = 0 · 081 probability of a 1 year delay [14-17] 1 · 83 days = 0 · 005 probability of a 1 year delay Used pre-intervention data and ratio of delay days "pre" and "post" intervention from [20] to obtain post-intervention estimate of delay days
Loss to follow up during diagnostic work-up 0 · 254 [21-24] (Assume that loss to follow up is the same for regardless of provider) 0 · 140 Used pre-intervention data and ratio of outcomes "pre" and "post" intervention from [19] to obtain post-intervention estimated of loss to follow up
DOTS Expansion for Treatment Incorrect treatment 0 · 791 [25] 0 · 129 [25] Scenario assumed that incorrect treatment was given regardless of DST availability
Non specific DOTS Expansion (NTP Strengthening) Initial access- inaccessible provider (ie · probability that patient seeks care with alternative provider that is inaccessible to interventions) 0 · 055 [14,26-31] 0 · 025 Intervention assumed to have same impact as in private sector
Private Sector interventions Incorrect diagnostic test ordered by private provider 0 · 622 [18] 0 · 362 [19]
Diagnostic delay (private sector only) 0 · 11 [14-17] (# days pre-intervention) 0 · 007 Used pre-intervention data and ratio of delay days "pre" and "post" intervention from [20] to obtain post-intervention estimate of delay days and then used ratio of outcomes in public vs private sector from [14] [27,32,33] to extrapolate estimate for public system to private system
Loss to follow up during diagnosis (private sector only) 0 · 254 [21-24] 0 · 140 Assumed to be same as in public sector (a 45% reduction). Used pre-intervention data and ratio of outcomes "pre" and "post" intervention from [19] to obtain post-intervention estimated of drop out
Incorrect treatment by private provider 0 · 771 [34] 0 · 126 Used pre-intervention data and ratio of outcomes "pre" and "post" intervention from [25] to obtain post-intervention estimate of incorrect treatment
HIV/ ART therapy programmes TB Death rate in HIV/TB co-infected 0 · 12 [35] 0 · 10 [35] [36,37] (see table S5 in Supplement appendix for more detail)
TB Relapse rate HIV/TB co-infected 0 · 16 [36] 0 · 01 [35] [36,37] (see table S5 in Supplement appendix for more detail)
TB Reactivation rate HIV/TB co-infected 0 · 0340 [38-40] 0 · 02 [41]
MDR-TB related interventions DST performed 0 · 2 Assumption 0 · 5 Assumption
MDR- loss to follow up rate in HIV negative cases 0 · 22 [36] 0 · 11 Assumption- reduce rate to 50%